Edition: International
Thursday 10 July, 2025
BREAKING NEWS

Shallow Earthquake of Magnitude 4.4 Jolts Delhi-NCR

  • News
    • Kochi
    • Trivandrum
    • Kozhikode
  • Sports
  • Business
  • Health
  • Entertainment
    • E24hrs
    • Cinema
    • Directors
    • Actors
  • Education
    • Career
  • Automobile
  • Personalities
    • Political Leaders
  • Religion
    • Christian
      • Catholic
      • Latin Catholic
      • Syro Malabar
    • Hindu
    • Islam
  • Environment
  • More
    • Food
    • Wellness
    • Lifestyle
    • Beauty & Fashion
    • Fitness
    • Mental Health
    • Yoga
    • Video
  • മലയാളം
BREAKING NEWS
100Days: Thirike, Neestream and Gopi Make their Way into the India Book of Records
Aalekh Foundation Announces 3rd Edition of the Aalekh Women Achievers Awards
The Israel Ministry of Tourism Successfully Concludes Largest Civilian Evacuation Operation
Bihar Police Bans Makeup for Women Officers on Duty
Shallow Earthquake of Magnitude 4.4 Jolts Delhi-NCR
AR Classroom of KSUM Startup Infusory at 121 Tribal Schools in Maharashtra
    • News
      • Kochi
      • Trivandrum
      • Kozhikode
    • Sports
    • Business
    • Health
    • Entertainment
      • E24hrs
      • Cinema
      • Directors
      • Actors
    • Education
      • Career
    • Automobile
    • Personalities
      • Political Leaders
    • Religion
      • Christian
        • Catholic
        • Latin Catholic
        • Syro Malabar
      • Hindu
      • Islam
    • Environment
    • More
      • Food
      • Wellness
      • Lifestyle
      • Beauty & Fashion
      • Fitness
      • Mental Health
      • Yoga
      • Video
    • മലയാളം
  • Health
  • This Blood Test May Predict Onset of Tuberculosis

    By NE Reporter on January 20, 2020

    LONDON:
    Researchers, including one of Indian-origin, have revealed a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives.

    For the findings, published in the journal Lancet Respiratory Medicine, researchers at University College London sought to identify which, if any, gene expression signatures in blood could be used to predict the disease at a very early stage and before symptoms Gene expression signatures are single or combined measurements of levels of specific gene products and are being tested in a range of diseases to aid diagnosis, prognosis or prediction of the response to treatment.

    Some are already being used to support the management of cancers, but none have reached the clinic in infectious diseases, such as tuberculosis (TB).

    “Our findings establish the gene signatures in blood which show most promise for identifying people who are at risk of disease,” said study author Mahdad Noursadeghi, Professor at University College London. “Future development of a blood test based on these findings could make an important contribution to efforts to reduce the impact and spread of this deadly infection,” Noursadeghi added.

    For this study, researchers initially conducted a systematic review of published gene signatures found to be present in blood samples from people with TB, compared to healthy individuals. From this, 17 candidate gene expression signatures for TB were identified, and tested in more than 1,100 blood samples in published data sets from South Africa, Ethiopia, The Gambia, and the UK. Scientists analysed samples from people who had no TB symptoms at the time they gave blood.

    Those people were then followed up to identify which participants developed TB in the subsequent months. Researchers found that eight of these signatures, including measurement of expression of a single gene, could predict the diagnosis of TB within three to six months, which falls within the accuracy required by the World Health Organisation (WHO) for new diagnostic tests.

    This accuracy was achieved, by revealing the patients” immune responses to bacteria before the symptoms of the disease develop.

    “The emergence of gene expression signature tests, which can aid diagnosis and early treatment, provides real hope for the management of infectious diseases,” said Indian-origin researcher and the study”s lead author Rishi Gupta.

    “In this study we identify multiple signatures to identify the onset of tuberculosis, which is extremely encouraging, potentially providing multiple targets for early detection,” Gupta added.

    Further development of these tests could help identify people who will benefit most from preventative antibiotic treatment, in order to reduce the occurrence of tuberculosis, the researchers said.

    NE Reporter

    antibioticsBlood Testdeadly infectiondiagnoistic testsearly detectiongene-expressioninfectious diseaseLancet Respiratory MedicinetuberculosisUniversity College LondonWorld Health Organisation

    more recommended stories

    • Naga Sadhu’s Recognized in France for Health Initiative Conducted at Maha Kumbh 2025

      MUMBAI:The revered Naga Sadhus have brought.

    • Fatty Liver No Longer Just a Lifestyle Disease: Experts Raise Alarm

      KOCHI:In a joint initiative by Amrita.

    • Complex Hernia Case Treated Successfully with Minimally Invasive Surgery

      KOCHI:A 52-year-old male patient, who had.

    • DKMS Foundation India Honours Stem Cell Donors

      KOCHI:Ahead of World Blood Cancer Day,.

    • Dangerously Low Oxygen Levels Normalized Through Complex Surgery

      THIRUVANANTHAPURAM:A complex surgery was successfully performed.

    • KSUM-backed Startup VitalView AI Flagged Chances of Nipah Incidence in Kerala

      KOCHI:Public health intelligence startup VitalView AI,.

    • Asthma Remains Underdiagnosed in 7 out of 10 Severe Cases

      KOZHIKODE:Marked by the GINA (the Global.

    • Aster Guardians Global Nursing Award Unveils Top 10 Finalists for 2025

      KOCHI:The Aster Guardians Global Nursing Award.

    • GenomeIndia Offers Long-term Benefit of Creating Healthy Posterity: Scientist

      THIRUVANANTHAPURAM:Country’s pioneering scientific project GenomeIndia will.

    • Researchers at RGCB Discover New Methods to Overcome Bacterial Resistance to Antibiotics

      THIRUVANANTHAPURAM: Researchers at the BRIC-Rajiv Gandhi.

    Live Updates

    • Aalekh Foundation Announces 3rd Edition of the Aalekh Women Achievers Awards
    • The Israel Ministry of Tourism Successfully Concludes Largest Civilian Evacuation Operation
    • Bihar Police Bans Makeup for Women Officers on Duty
    • Shallow Earthquake of Magnitude 4.4 Jolts Delhi-NCR
    • AR Classroom of KSUM Startup Infusory at 121 Tribal Schools in Maharashtra

    NewsExperts.in

    • മലയാളം
    • മലയാളം

    What’s New ?

    • Aalekh Foundation Announces 3rd Edition of the Aalekh Women Achievers Awards
    • The Israel Ministry of Tourism Successfully Concludes Largest Civilian Evacuation Operation
    • Bihar Police Bans Makeup for Women Officers on Duty
    • Shallow Earthquake of Magnitude 4.4 Jolts Delhi-NCR
    • AR Classroom of KSUM Startup Infusory at 121 Tribal Schools in Maharashtra

    Newsexperts.in - powered by Klickevents Infosolutions (P) LTD